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Related Concept Videos

Brain Imaging01:14

Brain Imaging

Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans),  magnetic resonance imaging (MRI),  functional magnetic resonance imaging (fMRI), and Transcranial Magnetic Stimulation (TMS).

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Related Experiment Video

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Targeting Neuronal Fiber Tracts for Deep Brain Stimulation Therapy Using Interactive, Patient-Specific Models
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Deep brain stimulation: technology at the cutting edge.

Rahul S Shah1, Su-Youne Chang, Hoon-Ki Min

  • 1Department of Neurological Surgery, Mayo Clinic, Rochester, MN, USA.

Journal of Clinical Neurology (Seoul, Korea)
|January 26, 2011
PubMed
Summary

Deep brain stimulation (DBS) is a proven therapy for neurological and psychiatric conditions like Parkinson's disease. Future advancements aim for intelligent closed-loop systems to enhance treatment precision and effectiveness.

Keywords:
Parkinson's diseasedeep brain stimulationmechanism of action

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Area of Science:

  • Neurosurgery
  • Neurology
  • Psychiatry

Background:

  • Deep brain stimulation (DBS) is a well-established surgical treatment.
  • Over 75,000 procedures have been performed globally.
  • DBS is effective for Parkinson's disease, tremor, dystonia, epilepsy, depression, Tourette's syndrome, and OCD.

Purpose of the Study:

  • To review current and emerging evidence for DBS in neurological and psychiatric conditions.
  • To discuss the technical and practical aspects of DBS surgery.
  • To explore future directions in DBS technology.

Main Methods:

  • Review of existing scientific literature and clinical evidence.
  • Analysis of technical and practical considerations for DBS procedures.
  • Discussion of potential technological advancements.

Main Results:

  • DBS is a validated treatment for a variety of movement and psychiatric disorders.
  • Current surgical techniques and applications are detailed.
  • Future technological evolution is contingent on mechanistic understanding and advanced tools.

Conclusions:

  • DBS is a critical therapeutic option for numerous neurological and psychiatric conditions.
  • Advancements in imaging, sensing, and understanding mechanisms are key for future DBS systems.
  • Intelligent closed-loop DBS holds promise for optimized neuromodulation and efficacy.