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A remarkably flexible and selective receptor for Ba2+ amplified from a hydrazone dynamic combinatorial library
Jörg M Klein1, Vittorio Saggiomo, Lisa Reck
1University Chemical Laboratory, University of Cambridge, Lensfield Road, Cambridge, UK CB2 1EW.
Abstract:
A new [2+2] tetra-hydrazone macrocyclic receptor was significantly amplified in a dynamic combinatorial library upon templation with alkaline earth metal ions. After optimisation the product could be isolated in 95% yield and its interaction with ions was investigated by NMR and UV-Vis spectroscopy.
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