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Published on: November 1, 2024
Reticulated acanthoma with apocrine differentiation.
Juan Carlos-Hiromi López1, Gulnara Taldibaeva, Katja Sperhake
1Department of Pathology, Universidad Nacional de Colombia, Bogotá, Colombia. jchiromi@hotmail.com
Journal of Cutaneous Pathology
|January 27, 2011
Summary
Reticulated acanthoma with apocrine differentiation (RAAD) is a rare skin neoplasm characterized by a unique reticulated pattern of keratinocytes. This report details a newly diagnosed case, contributing to the limited literature on this adnexal tumor.
Area of Science:
- Dermatopathology
- Oncology
- Histopathology
Background:
- Reticulated acanthoma with apocrine differentiation (RAAD) is a rare adnexal neoplasm.
- First described in 1998, RAAD exhibits a reticulated pattern of keratinocytes with potential apocrine, sebaceous, and follicular differentiation.
- Few cases have been documented since its initial description.
Purpose of the Study:
- To report a case of RAAD.
- To discuss diagnostic criteria for RAAD.
- To review differential diagnoses for RAAD.
Main Methods:
- Histopathological examination of an excised skin lesion.
- Analysis of clinical presentation and patient demographics.
- Comparison with established criteria for adnexal neoplasms.
Main Results:
- A 46-year-old male presented with a leg lesion.
- Histopathology confirmed features diagnostic of RAAD.
- The lesion displayed a reticulated pattern with evidence of differentiation.
Conclusions:
- RAAD is a rare adnexal neoplasm with distinct histopathological features.
- Accurate diagnosis requires careful consideration of differentiation markers.
- Further case reports are needed to fully characterize RAAD.
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