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Updated: Jun 5, 2026

Changes in Mammary Gland Morphology and Breast Cancer Risk in Rats
Published on: October 16, 2010
Classification and grading of canine mammary tumors
M Goldschmidt1, L Peña, R Rasotto
1Laboratory of Pathology and Toxicology, University of Pennsylvania, School of Veterinary Medicine, 3900 Delancey Street, Philadelphia, PA 19104, USA. goldsch@vet.upenn.edu
Abstract:
Mammary neoplasms are the most common neoplasm in female dogs. Two histologic classification systems for canine mammary tumors and dysplasias have been published: the first in 1974 and a modification in 1999. This article provides a brief overview of the two histologic classification systems. Since the publication of the second system, several new histologic subtypes of canine mammary neoplasms have been described. These have been incorporated into the proposed new classification system. This article also compares the grading systems for canine mammary carcinomas and their use for prognosis, along with the histologic classification.
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