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An Immunohistopathologic Study to Profile the Folate Receptor Beta Macrophage and Vascular Immune Microenvironment in Giant Cell Arteritis
Published on: February 8, 2019
[Visual hallucinations and giant cell arteritis: the Charles Bonnet syndrome]
J Bloch1, S Morell-Dubois, E Koch
1Service de médecine interne, hôpital Huriez, CHRU de Lille, Lille cedex, France.
Insights
Giant cell arteritis patients experiencing visual hallucinations may have Charles Bonnet syndrome, not a disease relapse. Early diagnosis is crucial for appropriate treatment and management.
Area of Science:
- Ophthalmology
- Neurology
- Rheumatology
Background:
- Diagnostic strategies for visual hallucinations are not well-defined.
- Giant cell arteritis diagnosis often assumes disease relapse in affected patients, necessitating prompt corticosteroid treatment.
- Charles Bonnet syndrome is an underrecognized cause of visual hallucinations, particularly in the elderly.
Observation:
- A case of an 87-year-old woman with a two-year history of giant cell arteritis is presented.
- The patient presented with a sudden onset of visual hallucinations.
- The patient met all diagnostic criteria for Charles Bonnet syndrome.
Findings:
- The patient's visual hallucinations were attributed to Charles Bonnet syndrome.
- This case highlights the importance of considering Charles Bonnet syndrome in the differential diagnosis of visual hallucinations in patients with giant cell arteritis.
- Misdiagnosis could lead to unnecessary or inappropriate treatment, such as corticosteroids for presumed giant cell arteritis relapse.
Implications:
- This case underscores the need for a broader differential diagnosis when evaluating visual hallucinations in patients with giant cell arteritis.
- Recognizing Charles Bonnet syndrome can prevent misdiagnosis and ensure appropriate patient management.
- Further research into the overlap and differentiation between these conditions is warranted.
Abstract:
In patients with visual hallucinations, diagnostic strategy is unclearly codified. In patients known to have giant cell arteritis, the main diagnostic assumption is disease relapse. Indeed, this should lead to rapid corticosteroid therapy. However, the Charles Bonnet syndrome, that is a poorly known etiology of visual hallucinations usually observed in elderly people, should be part of the differential diagnosis. We report a 87-year-old woman, with a 2-year history of giant cell arteritis who was admitted with an acute onset of visual hallucinations and who met all the criteria for Charles Bonnet syndrome.
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