Related Experiment Video
Updated: Jun 4, 2026

In Vitro Modeling of Down Syndrome Neurogenesis Using Human-Induced Pluripotent Stem Cells
Published on: March 7, 2025
Patient with Down syndrome and implant therapy: a case report
Mônica Regina Pereira Senra Soares1, Fernanda Oliveira de Paula, Maria das Graças Afonso Miranda Chaves
1Dental School, Federal University of Juiz de Fora, Juiz de Fora, MG, Brazil. monica_pereirasenra@hotmail.com
Abstract:
Patients with Down syndrome may not be cooperative during dental treatment and, in cases of complex treatment, it is necessary to use oral or inhaled sedation and/or general anesthesia, which represent safe and efficient treatment resources. There are few reports about oral rehabilitation with dental implants in patients with Down syndrome in the literature. This paper presents the case of a patient with Down syndrome and moderate mental retardation who suffered avulsion of the maxillary left central incisor after a fall, and was treated by means of a single dental implant with immediate load carried out under general anesthesia. After 4 years of follow up, there has been improvement in the sleep obstructive apnea syndrome due to the use of a tongue crib adapted for providing esthetics and preserving the implant placed.

