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Data Acquisition and Analysis In Brainstem Evoked Response Audiometry In Mice
Published on: May 10, 2019
Standardization of brainstem auditory evoked potential using a new device.
Ilka do Amaral Soares1, Pedro de Lemos Menezes, Aline Tenório Lins Carnaúba
1Departamento de Fonoaudiologia, Universidade Federal de São Paulo. ilkaamaralsoares@gmail.com
Pro-Fono : Revista De Atualizacao Cientifica
|January 29, 2011
Summary
This study standardized Brainstem Auditory Evoked Potential (BAEP) using a new device (NDD), finding similar results to existing equipment. Normal BAEP values were established for adults, with women showing statistically lower latencies.
Area of Science:
- Audiology
- Neurophysiology
- Biomedical Engineering
Background:
- The Brainstem Auditory Evoked Potential (BAEP) is a crucial diagnostic tool.
- Standardization of BAEP measurements is essential for reliable clinical interpretation.
- A new device (NDD) was developed in Brazil for BAEP assessment.
Purpose of the Study:
- To standardize Brainstem Auditory Evoked Potential (BAEP) responses using a newly developed device (NDD).
- To compare BAEP measurements obtained with the NDD against a conventional device (EP15/Interacoustics).
- To establish normative BAEP values for normal-hearing adults.
Main Methods:
- BAEP analysis included absolute latencies, interpeak intervals, and wave amplitudes.
- The study involved 91 normal-hearing adults and 15 adults with bilateral neurosensory hearing loss.
- Standardized parameters were used: 80 dB nHL click, 13.1 Hz frequency, 100 µs duration, rarefied polarity, 10 ms window, 100-3000 Hz bandpass filter.
Main Results:
- Normal-hearing individuals (n=76) using the NDD showed specific mean latencies and interpeaks (e.g., Wave V=5.53 ms).
- Statistically significant gender differences were observed in absolute latencies (Waves III, V) and interpeaks (I-III, I-V), with lower latencies in women.
- No significant differences were found in BAEP latencies between the NDD and the EP15/Interacoustics device within the same individuals.
Conclusions:
- The NDD effectively produced reliable BAEP components in normal-hearing subjects.
- BAEP latencies measured with the NDD were comparable to those obtained with the EP15/Interacoustics device.
- Normative BAEP values for normal-hearing adults were successfully established using the NDD.
