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Free terminal time optimal control problem of an HIV model based on a conjugate gradient method

Taesoo Jang1, Hee-Dae Kwon, Jeehyun Lee

  • 1Department of Mathematics, Inha University, Yonghyundong, Namgu, Incheon, 402-751, Republic of Korea. iamnumber2@inha.ac.kr

Bulletin of Mathematical Biology
|January 29, 2011
PubMed
Summary

This study identifies optimal multidrug therapy and treatment durations for human immunodeficiency virus (HIV) type 1. Mathematical modeling shows dynamic therapy can achieve long-term HIV control and a strong immune response post-treatment.

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