Related Experiment Video
Updated: Jun 4, 2026

Protrusion Force Microscopy: A Method to Quantify Forces Developed by Cell Protrusions
Published on: June 16, 2018
Atomic force microscopy: a tool to analyze the structural organization of pathogenic protozoa
Wanderley de Souza1, Gustavo M Rocha
1Laboratório de Ultraestrutura Celular Hertha Meyer, Instituto de Biofísica Carlos Chagas Filho and Instituto Nacional de Ciência e Tecnologia em Biologia Estrutural e Bioimagens - Universidade Federal do Rio de Janeiro, Rio de Janeiro 21941-902, Brasil. wsouza@biof.ufrj.br
Abstract:
The fine structure of parasitic protozoa has been the subject of intense investigation with the use of electron microscopy. The recent development of atomic force microscopy (AFM) and all of the techniques associated with AFM has created new ways to further analyze the structure of cells. In this review, the various, presently-available modalities of AFM are discussed, as well as the results obtained in analysis of: (i) the structure of intact and detergent-extracted protozoa; (ii) the surface of infected cells; (iii) the structure of parasite macromolecules; (iv) the measurement of surface potential; and (v) force spectroscopy, the measurement of elasticity and ligand-receptor interactions.
More Related Videos
05:34Contact Mode Atomic Force Microscopy as a Rapid Technique for Morphological Observation and Bacterial Cell Damage Analysis
Published on: June 30, 2023
14:13Atomic Force Microscopy of Red-Light Photoreceptors Using PeakForce Quantitative Nanomechanical Property Mapping
Published on: October 24, 2014
Related Concept Videos
Atomic Force Microscopy
The AFM Probe
The probe is regarded as the heart of any AFM setup and comprises the...
Overview of Microscopy Techniques
Studying the Cytoskeleton
Two-Dimensional Microscopy in Microbiology