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A new, low-incidence red cell antigen (HOFM), associated with depressed C antigen
J J Hoffmann1, M A Overbeeke, H Kaita
1Department of Clinical Laboratories, Catharina Hospital, Eindhoven, The Netherlands.
Vox Sanguinis
|January 1, 1990
Abstract:
A case of mild hemolytic disease of the newborn is presented which was caused by an antibody to a hitherto unknown antigen of low incidence. This antigen, now designated as HOFM (ISBT number 700050) was detected in 6 relatives, and in all of them, it was associated with an unusually weakened expression of C antigen. The serological data indicate that HOFM may be part of the Rh system, but the genetic data, although supportive of this interpretation, are inconclusive.