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Application of RNAi and Heat-shock-induced Transcription Factor Expression to Reprogram Germ Cells to Neurons in C. elegans
Published on: January 1, 2018
Codon adaptation-based control of protein expression in C. elegans
Stefanie Redemann1, Siegfried Schloissnig, Susanne Ernst
1Max Planck Institute of Molecular Cell Biology and Genetics, Dresden Germany.
Nature Methods
|February 1, 2011
Abstract:
We present a method to control protein levels under native genetic regulation in Caenorhabditis elegans by using synthetic genes with adapted codons. We found that the force acting on the spindle in C. elegans embryos was related to the amount of the G-protein regulator GPR-1/2. Codon-adapted versions of any C. elegans gene can be designed using our web tool, C. elegans codon adapter.
