Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Disorders of Hemostasis

Disorders of Hemostasis

Hemostasis, the process that stops bleeding after a blood vessel injury, is crucial for maintaining the integrity of the circulatory system. However, disorders of hemostasis can disrupt this delicate balance, leading to either excessive clotting or bleeding. These disorders can be broadly classified into thromboembolic disorders and bleeding disorders.
Thromboembolic Disorders
Two factors primarily cause thromboembolic conditions.

Venous Thrombosis IV: Nursing Management

Venous Thrombosis IV: Nursing Management

Nursing management begins with a thorough assessment of the patient's health history. Key factors include trauma to veins, peripherally inserted central catheters, varicose veins, recent pregnancy or childbirth, surgery, bacteremia, prolonged bed rest, atrial fibrillation, COPD, heart failure, cancer, coagulation disorders, myocardial infarction, spinal cord injury, stroke, prolonged travel, recent bone fractures, and dehydration. Review medication intake, particularly oral contraceptives,...

Changes in Skin Color: Clinical Perspectives

Changes in Skin Color: Clinical Perspectives

The first thing a clinician sees is the skin, so the examination of the skin should be part of any thorough physical examination. Most skin disorders are relatively benign, but a few, including melanomas, can be fatal if untreated. A couple of the more noticeable disorders, albinism and vitiligo, affect the appearance of the skin and its accessory organs.
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...

Cardiovascular System Abnormal Findings I: Inspection and Palpation

Cardiovascular System Abnormal Findings I: Inspection and Palpation

In a cardiovascular examination, inspection and palpation are crucial for identifying abnormalities.
Abnormal findings observed during an inspection

Disorders of the Female Reproductive System

Disorders of the Female Reproductive System

The female reproductive system can be affected by several disorders, including Premenstrual Syndrome (PMS), Premenstrual Dysphoric Disorder (PMDD), endometriosis, and various forms of cancer. PMS and PMDD are cyclical conditions that cause physical and emotional distress, with symptoms that include edema, mood swings, and food cravings. PMDD is a more severe form of PMS characterized by increased symptom severity that peaks during the luteal phase and tends to improve or resolve shortly after...

Flail Chest-I

Flail Chest-I

Overview of Flail Chest
Flail chest is a severe and potentially life-threatening condition characterized by the fracture of three or more adjacent ribs in multiple places. It is most commonly caused by direct impacts and trauma, such as motor vehicle accidents or injuries from a steering wheel impact. It can also occur due to falls in elderly individuals with osteoporosis, or assaults involving sharp objects.
Pathophysiology
The pathophysiology of flail chest is complex, involving fractures of...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Diffusion MRI improves the accuracy of preoperative diagnosis of common pediatric cerebellar tumors among reviewers with different experience levels.

AJNR. American journal of neuroradiology·2013

Same author

Functional and molecular imaging: applications for diagnosis and staging of localised prostate cancer.

Clinical oncology (Royal College of Radiologists (Great Britain))·2013

Same author

Interleukins 1beta, 6, 8 and tumour necrosis factor alpha do not induce platelet activation.

Transfusion medicine (Oxford, England)·2001

Same author

Quantification of platelet activation status by analyzing P-selectin expression.

Biochemical and biophysical research communications·2000

Same author

Flow cytometric parameters for characterizing platelet activation by measuring P-selectin (CD62) expression: theoretical consideration and evaluation in thrombin-treated platelet populations.

Biochemical and biophysical research communications·2000

Same author

Management of chronic autoimmune thrombocytopenic purpura (ITP) in adults.

Transfusion science·1999

Search research articles

Related Experiment Video

Updated: Jun 4, 2026

Human Subcutaneous Adipose Tissue Sampling Using a Mini-Liposuction Technique

Human Subcutaneous Adipose Tissue Sampling Using a Mini-Liposuction Technique

Published on: September 27, 2021

Easy bruising in women.

Canadian Family Physician Medecin De Famille Canadien

|February 1, 2011

Summary

Easy bruising in women presents a diagnostic challenge. Initial screening tests like platelet count and coagulation times help identify potential bleeding disorders, guiding further investigation when necessary.

Area of Science:

Internal Medicine
Hematology

Background:

Easy bruising is a common complaint among women presenting to family physicians.
While often benign, easy bruising can pose diagnostic challenges.

Purpose of the Study:

To outline an approach for evaluating women with easy bruising.
To identify key diagnostic steps and screening tests for bleeding disorders.

Main Methods:

Detailed patient history and physical examination are crucial initial steps.
Screening laboratory tests include platelet count, prothrombin time, partial thromboplastin time, and bleeding time.
Further investigation at a specialized hemostasis center is indicated for abnormal screening tests or significant bleeding history.

Main Results:

Related Experiment Videos

Last Updated: Jun 4, 2026

Human Subcutaneous Adipose Tissue Sampling Using a Mini-Liposuction Technique

Human Subcutaneous Adipose Tissue Sampling Using a Mini-Liposuction Technique

Published on: September 27, 2021

Most women with easy bruising have normal findings upon investigation.
Screening tests effectively rule out significant bleeding problems or identify the affected hemostatic mechanism.
Abnormal screening results or a history of bleeding necessitate specialized, extensive evaluation.

Conclusions:

A systematic approach combining clinical assessment and targeted screening tests is effective for evaluating easy bruising in women.
Early identification of potential bleeding disorders ensures appropriate management and referral when needed.