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Updated: Jan 1, 2026

Author Spotlight: Advancing SERS Technology: Au@Carbon Dot Nanoprobes for Label-Free Analysis and Imaging
Published on: June 9, 2023
Carbon-bonded silver nanoparticles: alkyne-functionalized ligands for SERS imaging of mammalian cells
David C Kennedy1, Craig S McKay, Li-lin Tay
1Steacie Institute for Molecular Sciences, National Research Council Canada, 100 Sussex Drive, Ottawa, K1A 0R6, Canada.
Abstract:
Silver nanoparticles bonded to terminal alkynes form stable particles in aqueous solution, produce strong SERS signals for molecular imaging that arise from the carbon-metal bond, and expand the scope of molecules that can be used to stably functionalize plasmonic particles for mammalian cell imaging applications. β-Lactams represent a class of biologically important molecules that can be adapted to SERS studies in this manner.

