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Updated: Jun 4, 2026
08:53
Localization, Identification, and Excision of Murine Adipose Depots
Published on: December 4, 2014
[Adipose tissue as an endocrine modulator: hormonal changes associated with obesity]
René Baudrand B1, Eugenio Arteaga U, Manuel Moreno G
1Departamento de Endocrinología, Facultad de Medicina, Pontificia Universidad Católica de Chile, Chile. rbaudrand@med.puc.cl
Revista Medica De Chile
|February 1, 2011
Summary
Increased adipose tissue disrupts hormone balance, affecting cortisol, androgens, growth hormone, and thyroid function. This review explores these endocrine disorders and their management.
Area of Science:
- Endocrinology
- Metabolic Research
Context:
- Adipose tissue is an active endocrine organ, secreting hormones that influence systemic metabolism.
- Obesity is linked to significant disruptions in endocrine homeostasis.
Purpose:
- To review hormonal disorders associated with increased adipose tissue.
- To examine the role of adipose tissue in modulating endocrine physiology, focusing on cortisol, androgens, growth hormone, and the thyroid axis.
- To discuss clinical implications for patient management and treatment.
Summary:
- Adipose tissue dysfunction in obesity alters the secretion and regulation of key hormones.
- Specific hormonal disruptions include dysregulation of cortisol, androgens, growth hormone, and the thyroid axis.
- Understanding these interactions is crucial for effective therapeutic strategies.
Impact:
- Provides a comprehensive overview of obesity-related endocrine dysfunctions.
- Highlights the need for integrated management approaches considering hormonal imbalances.
- Informs clinical practice for patients with increased adipose tissue and associated hormonal disorders.
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