Related Experiment Video
Updated: Jun 4, 2026

Isolation of Mouse Respiratory Epithelial Cells and Exposure to Experimental Cigarette Smoke at Air Liquid Interface
Published on: February 21, 2011
Short term effect of hubble-bubble smoking on voice
A-L Hamdan1, A Sibai, L Mahfoud
1Department of Otolaryngology - Head and Neck Surgery, American University of Beirut Medical Center, Beirut, Lebanon. alhamdan@svclb.com
Hubble-bubble smoking, even for 30 minutes, can negatively impact voice quality. It leads to lower vocal pitch and increased laryngeal secretions and vocal fold vasodilation.
Area of Science:
- Otolaryngology
- Speech and Voice Science
Background:
- Hubble-bubble smoking is a prevalent practice with potential health implications.
- The effects of traditional cigarette smoking on voice are well-documented, but less is known about hubble-bubble smoking.
Purpose of the Study:
- To evaluate the immediate effects of hubble-bubble smoking on voice parameters.
- To assess changes in vocal fold appearance and acoustic voice measures post-smoking.
Main Methods:
- A prospective study involving 18 non-dysphonic subjects with a history of hubble-bubble smoking.
- Acoustic analysis and laryngeal video-stroboscopy were performed before and 30 minutes after smoking.
Main Results:
- No significant vocal fold erythema was observed.
- Mild vocal fold edema was present in some subjects both before and after smoking.
- Acoustic analysis revealed a drop in habitual pitch, fundamental frequency, and voice turbulence index, along with an increased noise-to-harmonics ratio post-smoking.
- Slight increases in laryngeal secretions and vocal fold vessel dilation were noted after smoking.
Conclusions:
- Thirty minutes of hubble-bubble smoking can induce short-term adverse effects on voice.
- These effects include decreased vocal pitch and increased laryngeal secretions and vocal fold vasodilation.
Related Concept Videos
Chronic Obstructive Pulmonary Disease III: Chronic Bronchitis Features
Stress Prevention and Stress Management Techniques IV
Larynx
Anatomy of the Larynx
The larynx consists of various components, including cartilage, muscles, and vocal cords. Its structure includes three large unpaired cartilages—the thyroid, cricoid, and epiglottis—and three smaller paired cartilages—the arytenoids, corniculates, and...
Chronic Obstructive Pulmonary Disease II: Emphysema
Factors Affecting Pulmonary Ventilation
Alveolar Surface Tension
The alveolar fluid lines the luminal surface of the alveoli and exerts a force called surface tension. This force is caused by the polar water molecules in the liquid being more strongly attracted to each...
Upper Respiratory Drugs: Antitussives, Expectorants, and Mucolytics
Antitussives include codeine, dextromethorphan (Robitussin), and benzonatate (Tessalon). Codeine and dextromethorphan exert their effects centrally by suppressing the cough reflex center in the medulla. Benzonatate operates peripherally within the respiratory tract by anesthetizing...

