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Incidental sinusitis in a pediatric intensive care unit
Brooke M Moore1, Karen Blumberg, Theresa A Laguna
1Division of Pediatric Pulmonology, Department of Pediatrics, University of Minnesota School of Medicine and Amplatz Children's Hospital, Minneapolis, MN, USA.
Insights
Nosocomial sinusitis is common in pediatric intensive care unit patients, with nearly half showing evidence of the condition. This highlights the need to consider sinusitis in diagnosing fever in these vulnerable children.
Area of Science:
- Pediatric critical care medicine
- Infectious diseases
- Radiology
Background:
- Nosocomial sinusitis is a known complication in adult intensive care units.
- Sinusitis can be an unrecognized cause of fever in intubated patients.
- The frequency of sinusitis in pediatric intensive care units (PICUs) remains understudied.
Purpose of the Study:
- To determine the incidental frequency of sinusitis in PICU patients compared to non-PICU patients.
- To assess if the presence of tubes (nasotracheal, nasogastric, orotracheal, or orogastric) increases sinusitis risk in PICU patients.
- To investigate if nasal tubes pose a higher sinusitis risk than oral tubes.
Main Methods:
- Retrospective chart review at a pediatric healthcare system.
- Analysis of head computed tomography (CT) scans in PICU and non-PICU patients.
- Sinusitis defined as Lund-MacKay score ≥5.
Main Results:
- 44.3% of PICU patients had sinusitis vs. 26.9% of non-PICU patients (p < .001).
- 69.4% of PICU patients with tubes had sinusitis vs. 29.4% without tubes (p < .001).
- Younger age and presence of a tube increased sinusitis probability (p < .001).
Conclusions:
- Nearly half of PICU patients undergoing head CTs showed incidental sinusitis.
- Over half of PICU patients with sinusitis were febrile within 48 hours of imaging.
- Sinusitis is common in PICU patients and should be considered in fever differential diagnoses.
Objective:
Intubation is a risk factor for nosocomial sinusitis in adult intensive care patients. Sinusitis in intubated adults can be an occult cause of fever. In children, nasal intubation may increase the risk of sinusitis. No pediatric study has determined the frequency of nosocomial sinusitis in the pediatric intensive care unit setting. We hypothesized that within a subset of patients who had head computed tomography imaging 1) the incidental frequency of sinusitis in pediatric intensive care unit patients exceeds the frequency in non-pediatric intensive care unit patients, 2) the frequency of sinusitis is greater in pediatric intensive care unit patients with a tube (nasotracheal, nasogastric, orotracheal, or orogastric) compared to those without a tube, and 3) nasal tubes confer an increased risk for sinusitis over oral tubes.
Design:
Retrospective chart review.
Setting:
Independent not-for-profit pediatric healthcare system.
Patients:
Pediatric intensive care unit and non-pediatric intensive care unit (inpatients hospitalized on medical-surgical wards) patients referred for head computed tomography.
Interventions:
None.
Measurements And Main Results:
Computed tomography images were scored using the Lund-MacKay staging system. Sinusitis was defined as a Lund-MacKay score ≥5. A total of 596 patients were studied, 395 (66.3%) in the pediatric intensive care unit. A total of 154 (44.3%) pediatric intensive care unit vs. 54 (26.9%) non-pediatric intensive care unit patients had sinusitis (p < .001). A total of 102 of 147 (69.4%) pediatric intensive care unit patients with a tube present had sinusitis vs. 73 of 248 (29.4%) patients without a tube present (p < .001). There was no difference in sinusitis based on tube location (p = .472). Of patients with sinusitis, 51.3% (81 of 158) compared to 39.4% (89 of 226) were febrile within 48 hrs of imaging (p = .021). A younger age or the presence of a tube increased the probability of sinusitis (p < .001).
Conclusions:
A total of 44.3% of our pediatric intensive care unit patients imaged for reasons other than evaluation for sinus disease had evidence of sinusitis, and 51.3% of these had fever. These findings raise the concern that sinusitis in pediatric intensive care unit patients is common and should be considered in the differential diagnosis of fever in pediatric intensive care unit patients.
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