[The luliberin test as a criterion for assessing the prospect of stimulating ovulation with pergonal]

Differentiated clinico-hormonal investigation using diagnostic LH-RH testing made it possible to reveal various conditions of patients with hypogonadotropic amenorrhea. The expression of clinical signs of hypoestrogenemia corresponded to a degree of hormonal insufficiency. The investigation permitted the evaluation of the prospects of perganol-stimulated ovulation and a choice of an optimum initial drug dose. Patients with moderate estrogenic insufficiency responding positively to LH-RH, were shown promising for perganol therapy. Pregnancy was noted in 86.4%, the initial drug dose was 2-3 ampules per day. In negative LH-RH testing pregnancy was noted in 12% of the patients only. The stimulation of ovulation in such patients should be started with a daily dose of 4-5 ampules of pergonal.