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Generalized acanthosis nigricans related to type B insulin resistance syndrome: a case report
Ki-Heon Jeong1, Seung-Joon Oh, Suk Chon
1Department of Dermatology, College of Medicine, Kyunghee University, Seoul, Korea.
Abstract:
Acanthosis nigricans (AN) is a cutaneous marker for many underlying states such as endocrine abnormality, obesity, certain drugs, and malignancy. Generalized AN is a rare condition and is commonly seen in adults with an underlying malignancy. The type B insulin resistance syndrome, a rare autoimmune disorder, is caused by the autoantibodies to the insulin receptor. Patients typically present with hyperglycemia but also may present with hypoglycemia. We report a rare case of a 36-year-old man with generalized AN and type B insulin resistance syndrome with hypoglycemia.
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