Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Brain Abscess l: Introduction

Brain Abscess l: Introduction

A brain abscess is a focal, intracerebral infection characterized by a localized collection of pus within the brain parenchyma, resulting from microbial invasion and the body’s inflammatory response. It progresses through stages: early and late cerebritis, followed by early and late capsule formation, reflecting tissue destruction, immune response, and eventual encapsulation.Etiology and PathogenesisCausative organisms vary with source and host factors, often involving polymicrobial infections,...

Local Anesthetics: Clinical Application as Epidural Anesthesia

Local Anesthetics: Clinical Application as Epidural Anesthesia

Epidural anesthetics are administered in the fat-filled epidural space, the outermost part of the spinal canal. This technique is commonly employed for pain management and anesthesia during lower abdomen and pelvis surgeries or labor and delivery.
Since epidural anesthetics can be infused through an epidural catheter, all types of drugs, including short-acting ones, can be administered. Chloroprocaine and lidocaine are examples of short and long-duration anesthetics, respectively. Bupivacaine...

Local Anesthetics: Clinical Application as Spinal Anesthesia

Local Anesthetics: Clinical Application as Spinal Anesthesia

Spinal anesthetics are given during lower abdomen and limb surgeries to block sensory and motor neurons. They are administered in the mid to low lumbar regions, primarily acting on the cauda equina's nerve roots. The blockade level depends on the local anesthetic (LA) concentration. Usually, low LA concentrations are sufficient to block sensory fibers, while only high LA concentrations block motor fibers. Other factors like injection volume and speed, the patient's posture, and the drug...

Bacterial Meningitis I: Introduction

Bacterial Meningitis I: Introduction

Bacterial meningitis is a severe, life-threatening inflammation of the meninges, particularly the pia mater and arachnoid mater, affecting the subarachnoid space, ventricles, and cerebrospinal fluid (CSF). If untreated, it can lead to significant neurological complications or death.Causative AgentsCommon pathogens vary with age and immune status. In adults, major organisms include Streptococcus pneumoniae, Neisseria meningitidis, and Haemophilus influenzae. Streptococcus agalactiae (group B...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Pediatric sinogenic and otogenic intracranial infections requiring neurosurgical intervention: a North American multicenter study in the era of COVID-19.

Journal of neurosurgery. Pediatrics·2026

Same author

Boundaries, Balance, and the Courage to Say No.

Pediatric neurosurgery·2026

Same author

A survey of the members of the American Society of Pediatric Neurosurgeons and factors associated with well-being.

Journal of neurosurgery. Pediatrics·2024

Same author

Editorial: Magnetic resonance-guided laser interstitial thermal therapy (MRg-LiTT) in the minimally invasive surgical treatment of epilepsy and/or brain neoplasms.

Frontiers in neurology·2024

Same author

Spina Bifida Global Learning Collaborative: Educating the next generation of clinicians, researchers, and advocates.

Journal of pediatric rehabilitation medicine·2023

Same author

Magnetic resonance imaging-guided stereotactic laser ablation therapy for the treatment of pediatric epilepsy: a retrospective multiinstitutional study.

Journal of neurosurgery. Pediatrics·2023

Search research articles

Related Experiment Video

Updated: Jun 4, 2026

A Neonatal Imaging Model of Gram-Negative Bacterial Sepsis

A Neonatal Imaging Model of Gram-Negative Bacterial Sepsis

Published on: August 12, 2020

Spinal epidural abscess in a neonate.

Zulma Tovar-Spinoza¹, Michelle Bode

¹Department of Neurosurgery, SUNY Upstate Medical University, 604 Jacobsen Hall, 750 East Adams Street, Syracuse, New York 13210, USA. tovarspz@upstate.edu

Journal of Neurosurgery. Pediatrics

|February 3, 2011

Summary

Spinal epidural abscess is a rare neonatal emergency. Prompt treatment in premature infants is crucial to prevent permanent spinal cord damage.

Area of Science:

Neurosurgery
Neonatal Medicine
Infectious Disease

Background:

Spinal epidural abscess (SEA) is a neurosurgical emergency requiring prompt diagnosis and intervention to prevent neurological deficits.
SEA is infrequently encountered in premature infants, presenting diagnostic challenges in this population.
Coagulase-negative Staphylococcus epidermidis bacteremia can lead to serious complications, including SEA.

Observation:

A case of a premature twin neonate presenting with complete paraparesis is described.
The neonate had a history of coagulase-negative Staphylococcus epidermidis bacteremia.
Diagnosis of spinal epidural abscess was established in the affected neonate.

Findings:

The neonate with SEA and paraparesis underwent surgical decompression.

More Related Videos

A Neonatal Mouse Spinal Cord Compression Injury Model

A Neonatal Mouse Spinal Cord Compression Injury Model

Published on: March 27, 2016

Non-Invasive Model of Neuropathogenic Escherichia coli Infection in the Neonatal Rat

Non-Invasive Model of Neuropathogenic Escherichia coli Infection in the Neonatal Rat

Published on: October 29, 2014

Related Experiment Videos

Last Updated: Jun 4, 2026

A Neonatal Imaging Model of Gram-Negative Bacterial Sepsis

A Neonatal Imaging Model of Gram-Negative Bacterial Sepsis

Published on: August 12, 2020

A Neonatal Mouse Spinal Cord Compression Injury Model

A Neonatal Mouse Spinal Cord Compression Injury Model

Published on: March 27, 2016

Non-Invasive Model of Neuropathogenic Escherichia coli Infection in the Neonatal Rat

Non-Invasive Model of Neuropathogenic Escherichia coli Infection in the Neonatal Rat

Published on: October 29, 2014

Treatment involved a single-level laminectomy and catheter irrigation.

The patient's condition was managed following the surgical intervention.

Implications:

Early diagnosis and surgical intervention are critical for managing spinal epidural abscess in neonates.
This case highlights the successful management of a rare neonatal neurosurgical emergency.
Effective treatment strategies for neonatal SEA can improve neurological outcomes.