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Salese to buffer saliva in elderly patients with xerostomia: a pilot study
Olga Kharevich1, Barry Shipman, Barry M Goldman
1Postgraduate Prosthodontics, Nova Southeastern University College of Dental Medicine, Ft. Lauderdale, FL, USA.
Summary
Salese lozenges effectively increase salivary pH towards neutral in patients with xerostomia (dry mouth). This pilot study suggests Salese provides a significant salivary pH shift within 10-30 minutes, lasting for hours.
Area of Science:
- Oral Medicine
- Biochemistry
Background:
- Xerostomia, or dry mouth, is often associated with acidic salivary pH.
- Patients on multiple medications are prone to xerostomia and altered oral pH.
Purpose of the Study:
- To evaluate the efficacy of Salese lozenges in altering salivary pH in xerostomic patients.
- To compare salivary pH before and after Salese lozenge use.
Main Methods:
- Pilot study involving ten subjects with xerostomia and acidic salivary pH.
- Saliva pH measurement at baseline and up to 120 minutes post-Salese lozenge use.
- Data analyzed using Analysis of Variance (ANOVA).
Main Results:
- Salese lozenges induced a shift towards a more neutral salivary pH within the first 30 minutes.
- The observed pH shift was sustained for at least 2 hours after initial use.
Conclusions:
- Salese lozenges demonstrate potential for use by xerostomic patients to achieve a more neutral salivary pH.
- Further research is recommended to explore the buffering capacity of Salese lozenges.
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