Related Experiment Video
Updated: Jun 4, 2026
High-throughput and Comprehensive Drug Surveillance Using Multisegment Injection-Capillary Electrophoresis-Mass Spectrometry
Published on: April 23, 2019
Reversing microcrystalline tests--an analytical approach to recycling of microcrystals from drugs of abuse
Leonie E Elie1, Mark G Baron, Ruth S Croxton
1University of Lincoln, School of Natural and Applied Sciences, Lincoln LN6 7TS, UK. lelie@lincoln.ac.uk
Abstract:
A combined analysis of microcrystalline tests followed by LC-MS or GC-MS analysis is described. Microcrystalline tests are shown to be non-destructive as addition products formed were easily dissociated after the application of an appropriate solvent. Subsequent analysis of the sample was done to quantify the recovery of the drug. Examples were performed using the date rape drug γ-hydroxybutyrate (GHB) and the synthetic opioid methadone.
