Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Pulmonary Tuberculosis IV01:26

Pulmonary Tuberculosis IV

Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
Pulmonary Tuberculosis V01:28

Pulmonary Tuberculosis V

Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the progression...
Pulmonary Tuberculosis I01:29

Pulmonary Tuberculosis I

Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Pulmonary Tuberculosis III01:31

Pulmonary Tuberculosis III

Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
Pulmonary Tuberculosis II01:28

Pulmonary Tuberculosis II

Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
Tuberculosis01:23

Tuberculosis

Tuberculosis (TB) remains a significant global health concern, primarily targeting the lungs and spreading through airborne transmission. Infection begins when aerosolized droplet nuclei, expelled by an individual with active TB, are inhaled by another person. These microscopic particles carry Mycobacterium tuberculosis, the causative agent of TB. Upon reaching the alveoli, the bacilli are engulfed by alveolar macrophages. However, due to their specialized lipid-rich cell wall, these pathogens...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Structural and functional mapping of protective human monoclonal antibodies against enterovirus A71.

Science advances·2026
Same author

Broad neutralization of influenza B hemagglutinin antibodies via receptor mimicry and glycan engagement.

Proceedings of the National Academy of Sciences of the United States of America·2026
Same author

Exosomes from human umbilical cord mesenchymal stem cells promote the growth of human hair dermal papilla cells.

PloS one·2025
Same author

Recommendation for immune prophylaxis of respiratory syncytial virus infection in children.

Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi·2025
Same author

Recommendation for the use of respiratory syncytial virus vaccines.

Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi·2025
Same author

Pneumococcal serotype prevalence and antibiotic resistance in children in South and Southeast Asia, 2012-2024.

Human vaccines & immunotherapeutics·2024

Related Experiment Video

Updated: Jun 4, 2026

Diagnosing Pulmonary Tuberculosis with the Xpert MTB/RIF Test
08:10

Diagnosing Pulmonary Tuberculosis with the Xpert MTB/RIF Test

Published on: April 9, 2012

Abdominal tuberculosis in children: a diagnostic challenge.

Yo-Spring Lin1, Yhu-Chering Huang, Tzou-Yien Lin

  • 1Department of Infectious Diseases, Ton-Yen General Hospital, Hsinchu, Taiwan.

Journal of Microbiology, Immunology, and Infection = Wei Mian Yu Gan Ran Za Zhi
|February 5, 2011
PubMed
Summary

Childhood abdominal tuberculosis (TB) presents with prolonged symptoms, often mimicking other conditions, leading to diagnostic delays. Early consideration of TB in children with fever, abdominal pain, and abnormal chest X-rays is crucial for timely diagnosis.

Related Experiment Videos

Last Updated: Jun 4, 2026

Diagnosing Pulmonary Tuberculosis with the Xpert MTB/RIF Test
08:10

Diagnosing Pulmonary Tuberculosis with the Xpert MTB/RIF Test

Published on: April 9, 2012

Area of Science:

  • Pediatric Infectious Diseases
  • Gastroenterology
  • Pulmonology

Background:

  • Abdominal tuberculosis (TB) is an uncommon but serious manifestation in children.
  • It often presents with vague, prolonged symptoms that can be misdiagnosed.
  • Delayed diagnosis is common, impacting patient outcomes.

Purpose of the Study:

  • To analyze the clinical characteristics, diagnostic challenges, and outcomes of childhood abdominal TB.
  • To identify key indicators for earlier diagnosis in a tertiary care setting.

Main Methods:

  • A retrospective review of 10 pediatric cases of abdominal TB over a 5-year period.
  • Data collected included demographics, symptoms, diagnostic workup (imaging, microbiology), and treatment outcomes.
  • Analysis of clinical presentations, laboratory findings, and radiological features.

Main Results:

  • The most frequent symptoms were fever, abdominal pain, and weight loss.
  • Diagnostic delays averaged 19 days post-hospitalization, with initial suspicion in only 30% of cases.
  • Common imaging findings included lymphadenopathy, ascites, and peritoneal thickening; abnormal chest radiography was noted in 90% of patients.
  • Mycobacterium tuberculosis was confirmed microbiologically in various samples.

Conclusions:

  • Abdominal TB should be suspected in children presenting with fever, abdominal pain, weight loss, and abnormal chest radiography.
  • Characteristic computed tomography findings and a history of TB exposure are vital diagnostic clues.
  • Prompt recognition and diagnosis are essential for effective management and improved outcomes in pediatric abdominal TB.