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Lung Capacity

Lung Capacity

The air in the lungs is measured in volumes and capacities. Lung volume measures reflect the amount of air taken in, released, or left over after a lung function, like a single inhalation. Lung capacity measures are sums of two or more lung volume measures.

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Related Experiment Video

Updated: Jun 4, 2026

Unilateral Lung Volume Analysis Using Micro-CT for Enhanced Assessment of Pulmonary Fibrosis in Preclinical Models

Unilateral Lung Volume Analysis Using Micro-CT for Enhanced Assessment of Pulmonary Fibrosis in Preclinical Models

Published on: June 20, 2025

Multi-scale lung modeling.

Merryn H Tawhai¹, Jason H T Bates

¹Auckland Bioengineering Institute, University of Auckland, Auckland, New Zealand.

Journal of Applied Physiology (Bethesda, Md. : 1985)

|February 5, 2011

Summary

This summary is machine-generated.

Multi-scale modeling in biology focuses on emergent phenomena, not exhaustive detail. Effective models judiciously select details relevant to the scale being studied, exemplified by lung computational models.

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Area of Science:

Computational Biology
Systems Biology
Physiology

Background:

Multi-scale modeling is increasingly important in understanding complex biological systems.
Integrative systems behavior is crucial for life, alongside genomic information.

Purpose of the Study:

To define the core principles of effective multi-scale biological modeling.
To illustrate these principles using computational models of the lung.

Main Methods:

Focusing on emergent phenomena rather than exhaustive inclusion of all biological details.
Applying principles to model organ-level functions like airway responsiveness and pulmonary vascular tone.

Main Results:

Multi-scale modeling requires selective inclusion of details relevant to the scale of interest.
Organ-level lung functions can be modeled without invoking every molecular or cellular event.

Conclusions:

The art of multi-scale modeling lies in knowing which biological details to omit.
Judicious selection of emergent phenomena is key to successful biological system modeling.