Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Validity limits of data on secretory IgA].

F Rosaschino1, M Vercelloni, R Torre

  • 1Istituto di Pediatria, Università di Milano.

Bollettino Dell'Istituto Sieroterapico Milanese
|January 1, 1990
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Sporadic Abdominal Wall Desmoid type Fibromatosis: treatment paradigm after thirty two years.

BMC surgery·2018
Same author

Feeding value of whole raw soya beans as a protein supplement for beef cattle consuming low-quality forages.

Journal of animal physiology and animal nutrition·2017
Same author

Abdominal wall reconstruction after desmoid type fibromatosis radical resection: Case series from a single institution and review of the literature.

International journal of surgery case reports·2017
Same author

Thin layered drawing media probed by THz time-domain spectroscopy.

The Analyst·2016
Same author

An ultra-rapid cryo-technique for complex organisms.

Cryobiology·2015
Same author

Supercooling and freezing processes in nanoconfined water by time-resolved optical Kerr effect spectroscopy.

Journal of physics. Condensed matter : an Institute of Physics journal·2015

Salivary Secretory Immunoglobulin A (sIgA) levels show high variability, questioning their use for evaluating respiratory infections or treatment responses. Emotional factors may influence sIgA production and secretion.

Area of Science:

  • Immunology
  • Respiratory Medicine
  • Genetics

Background:

  • Secretory Immunoglobulin A (sIgA) is a key component of mucosal immunity.
  • Titration of sIgA in saliva has been explored in various clinical contexts.

Purpose of the Study:

  • To investigate sIgA levels in respiratory tract infections and after Erythromycin treatment.
  • To assess sIgA levels post-surgery and explore potential hereditary predispositions to high sIgA.
  • To understand the variability of sIgA levels in saliva.

Main Methods:

  • Radial immunodiffusion technique used for sIgA titration in saliva and expectoration.
  • Studies conducted on pediatric and adult groups, including those with acute/chronic respiratory infections, post-treatment, and post-surgery.
  • Longitudinal sIgA monitoring in a healthy individual.

Related Experiment Videos

Main Results:

  • High variability in sIgA levels was observed across different groups and situations.
  • This variability cast doubt on the utility of salivary sIgA for the intended evaluations.
  • Consistent high variability was confirmed even in a healthy individual over ten days.

Conclusions:

  • The significant variability of salivary sIgA levels limits their application in assessing respiratory infections, treatment efficacy, or surgical outcomes.
  • Psychological and emotional factors are hypothesized to influence IgA and sIgA production, mobilization, and secretion, contributing to observed variability.