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Updated: Jun 4, 2026

A Point-of-Care Method with Integrated Decision Support Tool to Estimate Anemia at Population Level
Published on: January 19, 2024
[Hemolytic anemia in adults: Main causes and diagnostic procedure]
Valentine Loustau1, Constance Guillaud, Loïc Garcon
1CHU Henri-Mondor, centre de référence pour les cytopénies auto-immunes de l'adulte, service de médecine interne, 94010 Créteil cedex, France.
Abstract:
Hemolytic anemia (HA) is not an exceptional situation in adults. While establishing the hemolytic mechanism of an anemia is usually rather easy, finding the etiology may be quite difficult as both some hereditary (corpuscular) and acquired causes of HA may occur during adulthood. The diagnosis of HA therefore requires a multiple step procedure taking into account both patient's and family history, a careful analysis of the blood smear and a direct antiglobulin test. Based on these first data, the diagnosis procedure may then require more specific tests whose indications are discussed in this review.
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