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Updated: Jun 4, 2026

Minimally Invasive Establishment of Murine Orthotopic Bladder Xenografts
Published on: February 11, 2014
[Bladder necrosis after an immediate post-operative mitomycin C instillation]
J Branchereau1, F Luyckx, M Hitier
1Service d'Urologie, CHU Hôtel-Dieu, 44000 Nantes, France.
Abstract:
Administration of intravesical chemotherapy by mitomycin C decreases the risk of recurrence in non-muscle-invasive bladder tumours. We report the case of a man, who presented a full bladder necrosis after an immediate adjuvant mitomycin C instillation. The failure of resection of the necrotic area led us to perform a total cystectomy with an intestinal reconstruction. A review of the literature showed four other cases of necrosis of the bladder or of lower urinary tract. In all cases the rules of early instillation were observed.
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