Related Experiment Video
Updated: Jun 4, 2026

Perturbations of Circulating miRNAs in Irritable Bowel Syndrome Detected Using a Multiplexed High-throughput Gene Expression Platform
Published on: November 30, 2016
Diagnosing irritable bowel syndrome: a changing clinical paradigm
Phillip K Henderson1, Jack A DiPalma
1Division of Gastroenterology, University of South Alabama College of Medicine, Mobile, AL 36693, USA.
Irritable bowel syndrome (IBS) is diagnosed using symptom criteria, not by excluding other conditions. Identifying IBS type, like diarrhea-predominant or constipation-predominant, guides effective patient management.
Area of Science:
- Gastroenterology
- Internal Medicine
Background:
- Irritable bowel syndrome (IBS) has historically been a diagnosis of exclusion.
- Accurate diagnosis is crucial for effective patient management and treatment.
Purpose of the Study:
- To highlight the importance of symptom-based criteria for diagnosing IBS.
- To emphasize the role of clinical tools and patient history in IBS diagnosis.
- To outline the subsequent steps in diagnostic evaluation and management.
Main Methods:
- Utilizing symptom-based criteria for initial IBS diagnosis.
- Employing meticulous patient history collection and diagnostic tools.
- Identifying alarm symptoms or signs.
- Characterizing bowel habit patterns (diarrhea-predominant or constipation-predominant).
Main Results:
- IBS can be positively identified through specific symptom criteria.
- Diagnostic tools enhance the accuracy of symptom collection.
- Distinguishing IBS subtypes is essential for guiding treatment.
Conclusions:
- IBS diagnosis should be based on positive symptom identification, not exclusion.
- A thorough history and appropriate tools are key to diagnosis.
- Classifying IBS subtype directs appropriate diagnostic evaluation and management strategies.
Related Concept Videos
Irritable Bowel Syndrome II: Clinical Features and Diagnostic Evaluation
Irritable Bowel Syndrome (IBS) is classified into subtypes based on the predominant bowel habits as determined by the Bristol Stool Form Scale (BSFS). The subtypes are:
Irritable Bowel Syndrome
Irritable Bowel Syndrome I: Introduction
IBS is a chronic condition that can persist over a long period or recur frequently.
The pathogenesis of IBS involves a complex interplay of the following factors:
Altered...
Irritable Bowel Syndrome III: Medical and Nursing Management
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the colonic...
Chronic Bowel Disorders: Introduction
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...