Related Experiment Video
Updated: Jun 4, 2026

Optimization of Synthetic Proteins: Identification of Interpositional Dependencies Indicating Structurally and/or Functionally Linked Residues
Published on: July 14, 2015
Explicitly searching for useful inventions: dynamic relatedness and the costs of connecting versus synthesizing
1Amsterdam School of Economics, University of Amsterdam, E2.39, Roetersstraat 11, 1018 WB Amsterdam, The Netherlands.
Abstract:
Inventions combine technological features. When features are barely related, burdensomely broad knowledge is required to identify the situations that they share. When features are overly related, burdensomely broad knowledge is required to identify the situations that distinguish them. Thus, according to my first hypothesis, when features are moderately related, the costs of connecting and costs of synthesizing are cumulatively minimized, and the most useful inventions emerge. I also hypothesize that continued experimentation with a specific set of features is likely to lead to the discovery of decreasingly useful inventions; the earlier-identified connections reflect the more common consumer situations. Covering data from all industries, the empirical analysis provides broad support for the first hypothesis. Regressions to test the second hypothesis are inconclusive when examining industry types individually. Yet, this study represents an exploratory investigation, and future research should test refined hypotheses with more sophisticated data, such as that found in literature-based discovery research.
Related Concept Videos
Creative Thinking
Divergent thinking is the...
Synthetic Biology
Golden rice
Golden rice is a genetically modified...
The Availability Heuristic
Social Exchange Theory
Social Exchange Theory
Reason and Intuition

