Related Experiment Video
Updated: Jun 4, 2026
10:35
Multimodal Imaging and Spectroscopy Fiber-bundle Microendoscopy Platform for Non-invasive, In Vivo Tissue Analysis
Published on: October 17, 2016
A novel ultrasmall composite optical fiberscope
Kiyoshi Oka1, Takeshi Seki, Akihiro Naganawa
1Quantum Beam Science Directorate, Japan Atomic Energy Agency, Tokai-mura, Ibaraki, Japan.
Surgical Endoscopy
|February 8, 2011
Summary
A new composite optical fiberscope (COF) enables precise laser surgery by allowing simultaneous visualization and treatment. This ultrasmall device facilitates intuitive targeting, improving accuracy in endoscopic procedures.
Area of Science:
- Medical Devices
- Surgical Technology
- Laser Surgery
Background:
- Endoscopic laser surgery faces challenges with accurate targeting due to 2D views and misalignment.
- A novel composite optical fiberscope (COF) integrates visualization and laser irradiation capabilities.
- The COF ensures identical orientation of the endoscope and laser fiber for intuitive aiming.
Purpose of the Study:
- To develop and evaluate an ultrasmall COF for simultaneous endoscopic visualization and laser treatment.
- To assess the COF's effectiveness in targeting and occluding blood vessels in vivo.
Main Methods:
- An ultrasmall (1.1-mm diameter) COF with a central laser fiber and surrounding imaging/illumination fibers was developed.
- Porcine mesenteric blood vessels were irradiated in vivo.
- Ultrahigh-speed and thermographic cameras recorded the laser irradiation, with blood flow and vessel diameter measurements.
Main Results:
- The COF allowed highly visible targeting and precise laser energy delivery.
- Laser irradiation effectively constricted and reduced vessel size, decreasing blood flow by 81.7%.
- Vessel diameter at the irradiated point reduced by approximately 46-48%, with successful vessel blockage confirmed.
Conclusions:
- The ultrasmall COF enables simultaneous diagnosis and treatment in endoscopic procedures.
- Intuitive targeting is achieved despite the device's small diameter, enhancing surgical precision.
- This device holds potential for various surgical applications requiring accurate, minimally invasive laser treatment.
