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Published on: September 9, 2012
A study of reported factor IX use around the world
J S Stonebraker1, P H B Bolton-Maggs, M Brooker
1North Carolina State University, College of Management, Raleigh, NC 27695-7229, USA. jeff_stonebraker@ncsu.edu
Summary
Factor IX (FIX) concentrate usage varies significantly by country, increasing with economic capacity. This trend suggests a future rise in FIX concentrate use for hemophilia B treatment.
Area of Science:
- Hematology
- Public Health
- Health Economics
Background:
- Hemophilia B treatment relies on replacement therapy with Factor IX (FIX) concentrates.
- Understanding global FIX usage patterns is crucial for optimizing patient care and resource allocation.
Purpose of the Study:
- To analyze reported Factor IX (FIX) concentrate usage across 90 countries.
- To investigate the relationship between national economies and FIX utilization.
Main Methods:
- Data on international units (IUs) of FIX used were collected from the Marketing Research Bureau and World Federation of Hemophilia.
- Analysis focused on country-by-country usage and per capita/per person metrics.
Main Results:
- Reported FIX use shows considerable variation across national economies, including high-income countries.
- FIX usage correlates positively with economic capacity and has increased over time.
- Consumption growth is more rapid in high-income nations, indicating widening disparities in hemophilia care.
Conclusions:
- FIX concentrate consumption is projected to increase globally, particularly in high-income countries.
- Metrics like IUs per capita and per person offer a comprehensive view of hemophilia care levels.
- Improved data collection and surveillance are vital for identifying patient needs and best practices in hemophilia B treatment.
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