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[The immune pathogenesis of lichen planus]
1Dental School, University of Athens.
To Helleniko Periodiko Gia Stomatike & Gnathoprosopike Cheirourgike
|June 1, 1990
Summary
Lichen planus, a chronic inflammatory skin condition, frequently affects oral tissues. This review critically examines the immunological mechanisms, including humoral and cellular immunity, implicated in its pathogenesis.
Area of Science:
- Dermatology
- Immunology
- Oral Medicine
Context:
- Lichen planus (LP) is a chronic inflammatory skin disease with unknown causes.
- Oral lesions occur in 25-35% of cases, sometimes without skin symptoms.
Purpose:
- To critically review the immunological pathogenesis of lichen planus.
- To explore the roles of humoral and cellular immunity in LP development.
Summary:
- Recent studies suggest an immune basis for lichen planus.
- Both humoral and cellular immune responses are implicated in the disease's pathology.
Impact:
- Provides a comprehensive overview of the immune mechanisms underlying lichen planus.
- Highlights the importance of immunological factors in understanding and potentially treating oral and skin lichen planus.