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Updated: Feb 11, 2026

Isolation, Processing and Analysis of Murine Gingival Cells
Published on: July 2, 2013
Localized gingival enlargements. A clinicopathological study of 1187 cases
P Tamiolakis1, E Chatzopoulou, F Frakouli
141 Amyclon Str, 11142 Lamprini, Athens, Greece, ptamiolakis@hotmail.com.
Background:
To describe the incidence, demographic and clinical features of 1187 localized gingival enlargements.
Material And Methods:
1187 cases of localized gingival enlargements diagnosed during a 20-year period were retrospectively collected. The patients' gender and age, as well as the main clinical features of the tumors were retrieved from the biopsy report forms.
Results:
The 1187 localized gingival enlargements represented 6.23% of 19.044 biopsies performed during the study period. 756 females and 427 males were affected with a mean age of 41.92±19.68 years. The lesions appeared as smooth (52.4%), granular (17.9%) or rough (13.16%) tumors, elastic (50.73%) or soft (29.56%) in consistency and red (60.8%), normal (28.58%) or white (8.17%) in color. The majority of the lesions (85.17%) were reactive in origin with pyogenic granuloma being the most common. In 1.1% of the cases a diagnosis of malignant lesion was rendered.
Conclusions:
All localized gingival enlargements should be submitted for microscopic examination because in approximately 1% of cases they are malignant.
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