[Experimental studies on wound healing of the jaw bone fracture]

The author has studied on wound healing of the jaw bone fractures in 5 Malaysian monkeys aging around 2 years and weighing about 3 Kg. For the experimental studies, fractures of the jaw bone in terms of oblique osteotomies from angle to sigmoid notch of the mandible of the Malaysian monkeys were made by using #700 fissure bur and reduced and fixed them in terms of interosseous wiring. The experimental animals were sacrificed on the 1st, 2nd, 3rd, 4th and 5th week thereafter, and the fracture sites were obtained to make microscopic slides stained with Hematoxylin-Eosin, and Van Gieson method. The results obtained were as follows: 1. The blood of hematoma situated in fractured crevice are getting replaced with granulation tissue 1 week after fracture. 2. The granulation tissue occurred in fractured crevice are getting replaced with connective tissue as bone matrix 2 weeks after fracture. 3. Immature new bone formation with bony trabeculation formed 3 weeks after fracture. 4. The secondary bony callus with abundant osteoblasts and osteocytes in bone matrix formed 4 weeks after fracture. 5. The fractured wound completely healed with a new bone formation 5 weeks after fracture.