Related Experiment Video
Updated: Jun 4, 2026

Disposable Dosators Intended for Dry Powder Delivery to Mice
Published on: August 18, 2023
Small dose... big poison
1Monash University, Southern Health, Victoria, Australia. george.braitberg@southernhealth.org.au
Background:
It is not possible to identify all toxic substances in a single journal article. However, there are some exposures that in small doses are potentially fatal. Many of these exposures are particularly toxic to children. Using data from poison control centres, it is possible to recognise this group of exposures.
Objective:
This article provides information to assist the general practitioner to identify potential toxic substance exposures in children.
Discussion:
In this article the authors report the signs and symptoms of toxic exposures and identify the time of onset. Where clear recommendations on the period of observation and known fatal dose are available, these are provided. We do not discuss management or disposition, and advise readers to contact the Poison Information Service or a toxicologist for this advice.
Related Concept Videos
Dose Response Curve: Conventional Versus Nonmonotonic
Drug Toxicity: Dose-Dependent Reactions
Dose Size and Dosing Frequency: Determination Methods
Pharmaceutical Poisoning: Potential Scenarios
Dose-Response Relationship: Potency and Efficacy
Prevention of Further Absorption of Poison

