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Updated: Jun 4, 2026
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Chemoselective Modification of Viral Surfaces via Bioorthogonal Click Chemistry
Published on: August 19, 2012
The first chemical synthesis of boronic acid-modified DNA through a copper-free click reaction
Chaofeng Dai1, Lifang Wang, Jia Sheng
1Department of Chemistry and Center for Biotechnology and Drug Design, Georgia State University, Atlanta, Georgia 30302-4098, USA.
Chemical Communications (Cambridge, England)
|February 9, 2011
Abstract:
The first chemical incorporation of the boronic acid group into DNA using a copper-free click reagent was reported. Compared with the PCR-based method, this approach allows for site-specific incorporation and synthesis on a larger scale.
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