Related Experiment Video
Updated: Jun 4, 2026

Generation of Two-color Antigen Microarrays for the Simultaneous Detection of IgG and IgM Autoantibodies
Published on: September 15, 2016
Defining specificities, genes, antigens, and antibodies- A matrix approach
1Department of Mathematics, University of Maine at Orono, 04469, Orono, Maine.
Abstract:
We study the consequences of assigning single letter symbols to operationally defined entities such as genes, antigens, specificities, and antibodies. If this is to be done and if reagents are not specific in recognizing the products of single genes or single antigens, then these entities must be defined by a 'definition matrix' to avoid mislabeling a matrix of data. A method is given whereby for a given matrix of data all possible definition matrices consistent with this data can be obtained. In particular, all the ways of labeling by the complex-complex code of Hirschfeld can be so obtained.
Related Concept Videos
Antigens Involved in Adaptive Immunity
Complete Antigens
Complete antigens possess both immunogenicity and reactivity.
Special Features of Adaptive Immunity
The primary cell types involved in adaptive immunity are T cells and B cells. Each type has a unique role in defending the body against pathogens. T cells are responsible for cell-mediated immunity. They identify and eliminate infected cells directly,...
Matrix Proteoglycans and Glycoproteins
Diversity of Antigen Receptors
Before encountering any antigen, lymphocytes express these receptors. On B cells, the antigen receptor is a membrane-bound antibody molecule called BCR; on T cells, it is a T cell receptor or TCR. B and T cell receptors are composed of two...
Cross-reactivity
Affinity and Avidity
