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Related Experiment Video

Updated: Jun 4, 2026

Real-time Monitoring of High Intensity Focused Ultrasound (HIFU) Ablation of In Vitro Canine Livers Using Harmonic Motion Imaging for Focused Ultrasound (HMIFU)

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Published on: November 3, 2015

Harmonic source wavefront aberration correction for ultrasound imaging.

Scott W Dianis¹, Olaf T von Ramm

¹Department of Biomedical Engineering, Duke University, Durham, North Carolina 27708-0281, USA.

The Journal of the Acoustical Society of America

|February 10, 2011

Summary

This study introduces a novel acoustic wavefront correction method using a low-frequency harmonic source. It significantly improves ultrasound imaging by restoring peak beam amplitude and contrast without prior target knowledge.

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Last Updated: Jun 4, 2026

Real-time Monitoring of High Intensity Focused Ultrasound (HIFU) Ablation of In Vitro Canine Livers Using Harmonic Motion Imaging for Focused Ultrasound (HMIFU)

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Evaluating Targeting Accuracy in the Focal Plane for an Ultrasound-guided High-intensity Focused Ultrasound Phased-array System

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Published on: March 6, 2019

Area of Science:

Ultrasound imaging
Acoustical physics
Medical imaging technology

Background:

Ultrasound imaging quality is often degraded by acoustic wavefront distortion.
Existing wavefront correction techniques may require a priori assumptions or transponders.
Need for robust methods to improve ultrasound image fidelity in diverse clinical scenarios.

Purpose of the Study:

To propose and evaluate a novel method for acoustic wavefront correction.
To achieve correction without prior knowledge of the target or external transponders.
To enhance ultrasound imaging performance by restoring beam amplitude and contrast.

Main Methods:

Utilizes a lower-frequency transmit to generate a known harmonic acoustical source in tissue.
Implements measurement and imaging steps on a Duke phased array system with a 2-D array.
Tests the method with electronic and physical aberrators across various imaging situations.

Main Results:

Achieved peak amplitude restoration ranging from 0.6 to 36.6 dB with a single correction.
Demonstrated visible improvement in standard phantom images post-correction.
Reported a 14 dB contrast improvement in phantom images after applying the correction method.

Conclusions:

The proposed method effectively corrects acoustic wavefront distortions in ultrasound imaging.
It offers significant improvements in peak beam amplitude and image contrast.
This technique, combined with prior methods, represents a significant advancement for clinical ultrasound imaging.