Related Experiment Video
Updated: Jun 4, 2026
13:32
DNA Extraction from Paraffin Embedded Material for Genetic and Epigenetic Analyses
Published on: March 26, 2011
Human DNA extraction methods: patents and applications
Francesco M Carpi1, Fabio Di Pietro, Silvia Vincenzetti
1School of Biosciences and Biotechnologies, University of Camerino, Camerino, Italy.
Recent Patents on DNA & Gene Sequences
|February 10, 2011
Summary
Advances in DNA extraction and purification from human specimens are crucial for biomedical research and genetic epidemiology. This review covers key patents and recent progress in DNA recovery from diverse biological samples.
Area of Science:
- Molecular Biology and Genetics
- Biomedical Research
- Forensic Science
Background:
- Since 1861, significant progress has been made in DNA handling and extraction techniques.
- The human genome's increasing study fuels pharmacogenomics and predictive genetic testing in medicine.
- DNA recovery from various biological samples is vital for genetic epidemiology.
Purpose of the Study:
- To review significant patents and recent advancements in DNA extraction and purification.
- To highlight the importance of DNA recovery from diverse human specimens for research applications.
Main Methods:
- Review of issued patents related to DNA extraction and purification.
- Analysis of recently published scientific literature on DNA recovery techniques.
- Examination of DNA extraction from various human biological samples (e.g., archived tissues, blood, serum, plasma).
Main Results:
- Extraordinary advances have been achieved in DNA extraction and purification methodologies.
- Diverse biological materials, including challenging archived samples, can yield nucleic acids.
- Emerging fields like genetic epidemiology increasingly rely on robust DNA recovery methods.
Conclusions:
- DNA extraction and purification are fundamental to modern biomedical research and applications.
- Continued innovation in DNA recovery techniques is essential for advancing fields like pharmacogenomics and genetic epidemiology.
- The review provides insights into the current landscape of DNA handling technologies and their impact.
Related Concept Videos
01:24DNA Isolation
DNA isolation protocols can be fast and straightforward or complex and time-consuming depending on the type and quality of DNA required for further processing. For example, plasmid DNA extraction is a bit more complicated than genomic DNA extraction because of the need for an appropriate lysis method to separate plasmid DNA from gDNA during isolation. However, for specific applications, such as long-range DNA sequencing that require a good yield of high- quality DNA samples, we need to follow...
01:34DNA Isolation
DNA from cells is required for many biotechnology and research applications, such as molecular cloning. To remove and purify DNA from cells, researchers use various methods of DNA extraction. While the specifics of different protocols may vary, some general concepts underlie the process of DNA extraction.