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Updated: Jun 4, 2026

Hybrid De Novo Genome Assembly for the Generation of Complete Genomes of Urinary Bacteria using Short- and Long-read Sequencing Technologies
Published on: August 20, 2021
Complete genome sequence of Cryptobacterium curtum type strain (12-3)
Cryptobacterium curtum, an oral opportunistic pathogen, has its complete genome sequenced. This study provides the first genome for the Coriobacteriaceae family, aiding in understanding its unique evolutionary position.
Area of Science:
- Microbiology
- Genomics
- Phylogenetics
Background:
- Cryptobacterium curtum is the type species of its genus and is phylogenetically distant within the Coriobacteriaceae family.
- This asaccharolytic, opportunistic pathogen is commonly found in the oral cavity and linked to dental infections like periodontitis.
Purpose of the Study:
- To describe the features of Cryptobacterium curtum.
- To present the first complete genome sequence and annotation for an actinobacterial family Coriobacteriaceae member.
Main Methods:
- Whole-genome sequencing of Cryptobacterium curtum.
- Bioinformatic analysis for genome annotation.
Main Results:
- The complete genome sequence of Cryptobacterium curtum was determined to be 1,617,804 bp.
- The genome contains a single replicon with 1364 protein-coding and 58 RNA genes.
- This represents the first complete genome sequence for the Coriobacteriaceae family.
Conclusions:
- The genome sequence provides valuable insights into the biology and evolutionary placement of Cryptobacterium curtum.
- This work contributes to the Genomic Encyclopedia of Bacteria and Archaea project, expanding genomic resources for underrepresented bacterial groups.
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