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Updated: Jun 4, 2026
06:18
An In Vivo Estrogen Deficiency Mouse Model for Screening Exogenous Estrogen Treatments of Cardiovascular Dysfunction After Menopause
Published on: August 13, 2019
Estrogens in the postmenopausal woman.
Canadian Family Physician Medecin De Famille Canadien
|February 10, 2011
Summary
Recent studies suggested a link between estrogens and cancer, but this review found no evidence to support this claim. Further research explores estrogens
Area of Science:
- Endocrinology and Oncology
- Medical Journalism Ethics
Background:
- Widespread media reports in 1975-1976 linked estrogens to cancer, primarily citing articles in the New England Journal of Medicine.
- Public health concerns and medical discourse were significantly influenced by these publications.
Purpose of the Study:
- To critically evaluate the scientific evidence for and against a causal relationship between estrogens and cancer.
- To review the established effects of estrogens on osteoporosis, thromboembolism, and arteriosclerosis.
Main Methods:
- Comprehensive review of existing scientific literature and published studies on estrogen-cancer relationships.
- Analysis of the evidence presented in key medical journal articles from 1975-1976.
Main Results:
- The review found no scientific basis to support the accusation of a causal link between estrogens and cancer.
- Established associations between estrogens and other conditions like osteoporosis, thromboembolism, and arteriosclerosis were examined.
Conclusions:
- The purported link between estrogens and cancer lacks sufficient scientific evidence.
- Estrogen's role in other physiological and pathological processes requires continued investigation.
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