Related Experiment Video
Updated: Jun 4, 2026

Robot-Assisted Laparoscopic Splenectomy In Children: A Case Report with Literature Review
Published on: March 27, 2026
Complications and outcomes of brown recluse spider bites in children
Jonathan J Hubbard1, Laura P James
1Dept. of Pharmacology and Toxicology, University of Arkansas for Medical Sciences, Little Rock, AR 72202, USA.
Insights
Brown recluse spider bites in children often cause inflammation and secondary infections. Systemic effects like hemolytic anemia, rhabdomyolysis, and acute kidney injury are common, necessitating careful monitoring.
Area of Science:
- Toxicology
- Pediatric Medicine
- Dermatology
Background:
- Brown recluse spider bites can lead to significant local and systemic illness.
- Limited data exists on the specific morbidity associated with these bites in pediatric populations.
Purpose of the Study:
- To review and characterize the local and systemic morbidity in children diagnosed with brown recluse spider bites.
- To identify common complications and outcomes in pediatric inpatients.
Main Methods:
- Retrospective review of inpatient medical records (n=26) over a 10-year period.
- Analysis of discharge diagnoses of 'spider bite' from a tertiary pediatric hospital.
- Evaluation of inflammatory responses, necrosis, secondary infections, and systemic effects.
Main Results:
- 85% of children exhibited an inflammatory response with necrosis; 77% had secondary cellulitis.
- Prevalent systemic effects included hemolytic anemia (50%), rhabdomyolysis (27%), and acute renal failure (12%).
- Hemolytic anemia showed a bimodal onset (early and late postbite), and 65% experienced major morbidity.
Conclusions:
- Brown recluse spider bites in children frequently cause significant local and systemic complications.
- Early recognition and management of local wound issues and systemic effects are crucial.
- Patient and family education, alongside vigilant inpatient monitoring, are vital for favorable outcomes.
Abstract:
Brown recluse spider bites may cause severe local and systemic morbidity, but data regarding morbidity in children are limited. This study reviewed inpatient medical records (n = 26; 10 years) with a discharge diagnosis of "spider bite" from a tertiary pediatric hospital. The majority (85%) of children had an inflammatory response accompanying necrosis, usually with signs of secondary cellulitis (77%). Hemolytic anemia (50%), rhabdomyolysis (27%), and acute renal failure (12%) were the most prevalent systemic effects. Hemolytic anemia was bimodal in distribution relative to the time-of-onset of the bite (early, 2.2 ± 0.4; late, 6.9 ± 1.5 days postbite, respectively; P = .004). Although no fatalities occurred in the population, 65% of children had major morbidity, including wound complications requiring surgical care and acute orbital compartment syndrome. The findings emphasize the importance of anticipatory patient/family education for outpatients and careful monitoring for systemic morbidity in inpatients. Timely and appropriate supportive care should yield favorable outcomes in most cases.
Related Concept Videos
Rocky Mountain Spotted Fever
Inflammatory Bowel Disease I: Ulcerative Colitis
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
Skin Cancer
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Healing II: Complications
Endocarditis II: Clinical Features of Infective Endocarditis
Chronic Bowel Disorders: Introduction
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
