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Published on: September 11, 2019
Renal Transplantation in HIV-Positive Recipients
1Division of Transplantation, Johns Hopkins Medical Institutions, 720 Rutland Avenue, Ross 765, Baltimore, MD, 21205, USA.
Abstract:
About 1% of all patients with end-stage renal disease in the United States are infected with HIV. With the introduction of highly active antiretroviral therapy (HAART), HIV death rates have declined 80%, and chronic diseases resulting from HIV have replaced opportunistic infections as the leading cause of death among HIV-infected patients. Traditionally, HIV infection has been considered an absolute contraindication to solid-organ transplantation. However, in the context of improved survival, the role for kidney transplantation among HIV-positive patients is currently being revisited. This article discusses long-term outcomes after kidney transplantation in the HAART era and management strategies for the HIV-positive kidney transplant recipient.
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