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An In vitro Model to Study Immune Responses of Human Peripheral Blood Mononuclear Cells to Human Respiratory Syncytial Virus Infection
Published on: December 10, 2013
The role of adenovirus in respiratory tract infections
Anjali N Kunz1, Martin Ottolini
1Department of Pediatrics, Uniformed Services University of the Health Sciences, Bethesda, MD, 20184, USA, akunz@usuhs.mil.
Abstract:
Adenovirus plays a significant role in respiratory tract disease in pediatric and adult patients. It has been linked to outbreaks and epidemics in various patient populations, resulting in considerable morbidity and mortality. In this article, we discuss the epidemiology, pathogenesis, respiratory tract illnesses and complications, and roles of potential treatment options. The role of the past oral adenovirus vaccine and the military implications of its withdrawal from routine use in military recruits is discussed as well.
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