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Drug-Resistant Malaria: The Era of ACT
Jessica T Lin1, Jonathan J Juliano, Chansuda Wongsrichanalai
1Division of Infectious Diseases, University of North Carolina School of Medicine, Chapel Hill, NC, 27514, USA, jesstlin@gmail.com.
Abstract:
As drug-resistant falciparum malaria has continued to evolve and spread worldwide, artemisinin-based combination therapies (ACT) have become the centerpiece of global malaria control over the past decade. This review discusses how advances in antimalarial drug resistance monitoring and rational use of the array of ACTs now available can maximize the impact of this highly efficacious therapy, even as resistance to artemisinins is emerging in Southeast Asia.
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