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An uncommon cause of postoperative bleeding

Giorgio Berlot1, Fabiana Tartamella, Rossana Bussani

  • 1Department of Anesthesia and Intensive Care, Cattinara University Hospital, Trieste, Italy. berlot@inwind.it

Blood Coagulation & Fibrinolysis : an International Journal in Haemostasis and Thrombosis
|February 12, 2011
PubMed

The postoperative phase can be associated with an increased risk of thrombosis and abnormal bleeding. We report the case of a patient admitted to our intensive care unit for postoperative monitoring who developed two episodes of hemorrhagic shock. A thromboelastogram performed with heparinase I digestion demonstrated the action of endogenous heparin-like substances whose presence was subsequently confirmed at the histological examination of the tumor. Heparinase-modified thromboelastography has proven to be an effective and rapid point-of-care coagulation test and in our case allowed early detection of circulating heparinoids.

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