[Morphological changes in thyroid tissue after preoperative fine-needle nodule biopsy]

The paper considers morphological changes in thyroid tissue after preoperative fine-needle biopsy of benign and malignant tumors at the above site in 5 patients. The found changes made the postoperative histological diagnosis of a tumor process difficult as; (a) there was total necrosis (2 cases of follicular tumor and papillary cancer from oxyphilic cells according to the data of a preoperative cytological study); (b) there were signs that mimicked those of invasive tumor growth in the proper fibrous capsules (2 cases of follicular adenomas); (c) there was abundant formation of fibrous tissue in the center of follicular adenoma. The paper discusses the rate and nature of the most common morphological changes induced by preoperative puncture biopsy.