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Updated: May 18, 2026

An Orthotopic Mouse Model of Anaplastic Thyroid Carcinoma
Published on: April 17, 2013
[Morphological features of papillary thyroid carcinoma with a focal tall-cell component]
Abstract:
The morphological features of papillary thyroid macro- and microcarcinomas of classical structure with the focal presence or absence of a tall-cell component were comparatively studied. Histological specimens of 55 neoplasms were examined in 53 patients. A trend was seen for the higher rate of regional metastasis in a group of tall-cell tumors. Additional studies of groups of patients matched for sex, age, and extrathyroid tumor extension are required to make a final conclusion on the metastatic potential and prognostic features of tumors with a tall-cell component. To solve this task, it is expedient to separate neoplasms with a focal tall-cell component from the bulk of classical papillary carcinomas.
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