Related Experiment Video
Updated: Jun 4, 2026

Correction of Presbyopia by Monocular Bi-Aspheric Ablation Profile
Published on: September 20, 2024
Cycloplegic refraction using atropine minidrops
1University Eye Hospital, Klinikum Steglitz, Hindenburgdamm 30, W-1000, Berlin 45, Federal Republic of Germany.
Abstract:
Topical application of atropine for cycloplegic refraction may be associated with alarming systemic reactions in infants and children. Cycloplegic refraction and pulse rate were compared after short-term minidrop application of atropine with a calibrated pipette (3 × 5 μl) and standard atropine application from commercial bottles (twice daily 30-36 μ1 for three days) in 30 hypermetropic eyes of children between 1 and 7 years of age. The mean spherical equivalents of cycloplegic refraction achieved after minidrop application was 0.23 D lower than that following standard application. In many cases, there was a substantial increase in pulse rate 90 minutes after atropine instillation, both from minidrops and from commercial bottles. Short-term minidrop application of atropine with a calibrated pipette may be used for cycloplegic refraction in infants and children if one wishes to reduce the total atropine dose.
Related Concept Videos
Open Angle Glaucoma: Treatment
Drugs such as carbonic anhydrase inhibitors, α2- and...
Ophthalmic Drug Delivery Systems
Angle Closure Glaucoma: Treatment
Focusing of Light in the Eye
Direct-Acting Cholinergic Agonists: Therapeutic Uses
Direct-Acting Cholinergic Agonists: Pharmacological Actions
