Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[von Willebrand's disease].

D Mezzano1, J Pereira, T Quiroga

  • 1Departamento de Hematología-Oncología, Escuela de Medicina, Universidad Católica de Chile, Santiago.

Revista Medica De Chile
|March 1, 1990
PubMed
Summary
This summary is machine-generated.

Von Willebrand

Related Experiment Videos

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Intradialytic nutritional intake and adherence perspective of a national and continuous meal model in a large hemodialysis patient cohort.

Clinical nutrition (Edinburgh, Scotland)·2026
Same author

Collapse of Nuclear Collectivity along the N=Z Line.

Physical review letters·2026
Same author

Clarifying the N,Z=14 Shells near the Drip Lines from the Spectroscopy of ^{22}Si and ^{21}Al.

Physical review letters·2026
Same author

Constraining the Synthesis of the Lightest p Nucleus ^{74}Se.

Physical review letters·2025
Same author

A Biophysical-Model-Informed Source Separation Framework For EMG Decomposition.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference·2025
Same author

Abrupt structural transition in exotic molybdenum isotopes unveils an isospin-symmetric island of inversion.

Nature communications·2025
Same journal

[Health Education for Informed Autonomy: When to Begin?]

Revista medica de Chile·2026
Same journal

[Open Atrial Transcatheter Mitral Valve Replacement for Mitral Annular Calcification: First Case Report in Chile].

Revista medica de Chile·2026
Same journal

[From Opinion to Structure: The Role of Different Types of Systematic Reviews Within the Evidence Synthesis Ecosystem].

Revista medica de Chile·2026
Same journal

[Neuropsychiatric Effects of Creatine: What Does the Preclinical and Clinical Evidence Conclude?]

Revista medica de Chile·2026
Same journal

[Ethical Issues in Early Serological Diagnosis of Alzheimer's Disease].

Revista medica de Chile·2026
Same journal

[Weight Recurrence After Bariatric Surgery: Definitions, Diagnosis, and Management Strategies. Part 1].

Revista medica de Chile·2026
See all related articles

Area of Science:

  • Hematology
  • Genetics
  • Molecular Biology

Context:

  • Von Willebrand's disease (VWD) is the most common inherited bleeding disorder.
  • It affects primary hemostasis, involving alterations in von Willebrand factor (VWF).
  • Patients exhibit variable muco-cutaneous bleeding.

Purpose:

  • To review the current understanding of VWD.
  • To highlight advances in molecular defect identification and laboratory diagnosis.
  • To address the challenges posed by emerging subtypes and variability.

Summary:

  • VWD is an autosomal disorder affecting VWF structure, function, or synthesis, leading to bleeding.
  • Recent years have seen progress in understanding genetic defects and diagnostic methods for VWD subtypes.
  • Despite advances, new VWD subtypes and significant genetic, clinical, and laboratory variability persist.

    • Impact:

    • Improved understanding of VWD pathogenesis.
    • Enhanced diagnostic capabilities for VWD subtypes.
    • Recognition of ongoing challenges in managing VWD due to its heterogeneity.