Related Experiment Video
Updated: Aug 13, 2026

10:02
Use of Rabbit Eyes in Pharmacokinetic Studies of Intraocular Drugs
Published on: July 23, 2016
[The study of resorcin eyedrops]
Abstract:
Seven resorcin eye drop formulas using various physico-chemical stabilizers, acid buffer solutions, antioxidants such as sodium pyrosulphite, cysteine and keodants such as EDTA--Na were prepared. A parallelism between the physico-chemical stability and local biological tolerance in rabbit eyes was found, fact demonstrating that the occurrence of some oxidation products are responsible for the biological intolerance manifestations. A pH under 5 is favourable to resorcin stability and local biological tolerance to resorcin eye drops.

